منابع مشابه
AMPEROMETRIC MICROBIOSENSOR FOR THE DETERMINATION OF CHOLINE
The construction and performance of an amperometric microbiosensor for the determination of choline chloride by immobilizing choline oxidase on a cellulose acetate membrane are described. The procedure of choline determination involved the electrochemical detection of enzymatically generated hydrogen peroxide. This microsensor has a linear response between 0.038-0.1 mM choline chloride. The...
متن کاملThe Choline Content of Rats on Various Choline-free Diets*
Choline synthesis in the rat is intimated by the fact that methionine can replace choline in preventing fatty livers (l), and by the observation that labeled methyl groups can be transferred from methionine to choline (2). However, the development of fatty livers (3) and of hemorrhagic kidneys (4) and the restricted growth (5, 6) in rats on low choline diets all suggest that preformed choline m...
متن کاملCholine transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency.
Choline acetyltransferase (ChAT), the enzyme that synthesizes the neurotransmitter acetylcholine (ACh), is thought to be present in kinetic excess in cholinergic neurons. The rate-limiting factor in ACh production is the provision of choline to ChAT. Cholinergic neurons are relatively unique in their expression of the choline transporter 1 (CHT1), which exhibits high-affinity for choline and ca...
متن کامل14 Choline 14 . 1 Choline in health and disease
Choline is a water-soluble nutrient that is often grouped with the vitamin B complex. However, its functions suggest it is more than just another vitamin. Choline is crucial for the normal function of all cells (Zeisel and Blusztajn, 1994). It is needed for the structural integrity and signaling functions of cell membranes; it directly affects cholinergic neurotransmission; it is the major sour...
متن کامل3 . 2 Choline and Its Products Acetylcholine and Phosphatidylcholine Choline
Choline, a quaternary amine obtained largely from the diet but also synthesized in the brain and, especially, liver, is an essential precursor of the neurotransmitter acetylcholine (ACh) and of the major membrane constituent phosphatidylcholine (PC). Plasma choline concentrations can vary over a fivefold range depending on the choline contents of the foods being digested. Since choline readily ...
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ژورنال
عنوان ژورنال: Nutrition Today
سال: 2007
ISSN: 0029-666X
DOI: 10.1097/01.nt.0000286155.55343.fa